Enoxaparin for prevention of unexplained recurrent miscarriage: a multicenter randomized double-blind placebo-controlled trial Short title: Enoxaparin for prevention of Recurrent Miscarriage
نویسندگان
چکیده
CIC-INSERM 1412, La Cavale Blanche Hospital, 29609 Brest, France EA 3878 (GETBO), CIC-INSERM 1412, La Cavale Blanche Hospital, 29609 Brest, France Division of Gynaecology, Lille University Hospital, 59037 Lille Division of Internal Medicine, Bretagne Sud Hospital, 56100 Lorient. Division of Gynaecology, Caen University Hospital, Clemenceau hospital, 14033 Caen Division of Gynaecology, Paris University Hospital, Necker Hospital, 75743 Paris Division of Gynaecology, Dijon University Hospital, Complexe du Bocage, 21079 Dijon Division of Gynaecology, Groupe hospitalier du sud de la Réunion, 97448 Saint Pierre
منابع مشابه
Enoxaparin for prevention of unexplained recurrent miscarriage: a multicenter randomized double-blind placebo-controlled trial.
It is common practice in many centers to offer antithrombotic medications to women with unexplained recurrent miscarriage, in the presence or absence of inherited thrombophilia. Although no benefit of aspirin vs placebo has been clearly demonstrated, a double-blind placebo-controlled trial on the effect of low-molecular-weight heparin is lacking. We enrolled 258 pregnant women with a history of...
متن کاملThromboprophylaxis for recurrent miscarriage in women with or without thrombophilia. HABENOX: a randomised multicentre trial.
Recurrent miscarriage affects 1-2% of women. In more than half of all recurrent miscarriage the cause still remains uncertain. Thrombophilia has been identified in about 50% of women with recurrent miscarriage and thromboprophylaxis has been suggested as an option of treatment. A randomised double-blind (for aspirin) multicentre trial was performed among 207 women with three or more consecutive...
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Background: Recurrent miscarriage (RM) affects 2-5% of pregnant women. Paternal lymphocyte immunotherapy is a common treatment for RM patients but the outcome has not been consistent. Therefore, combined therapy with other immunosuppressive drugs such as 1 a, 25-dihydroxy-vitamin-D3 (vitamin D3) may improve the outcome. Objectives: To investigate the effect of vitamin D3 on the balance of two...
متن کاملAspirin or anticoagulants for treating recurrent miscarriage in women without antiphospholipid syndrome.
BACKGROUND Since hypercoagulability might result in recurrent miscarriage, anticoagulant agents could potentially increase the live-birth rate in subsequent pregnancies in women with either inherited thrombophilia or unexplained recurrent miscarriage. OBJECTIVES To evaluate the efficacy and safety of anticoagulant agents, such as aspirin and heparin, in women with a history of at least two mi...
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BACKGROUND Venous thromboembolic diseases are treated initially with low molecular weight heparin followed by oral coumarins. OBJECTIVES To investigate an orally available direct thrombin inhibitor for the acute treatment of venous thromboembolism as well as for prophylaxis of recurrent events. METHODS The direct thrombin inhibitor ximelagatran was compared with subcutaneous LMW heparins fo...
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